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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
28.48
Human Site:
T378
Identified Species:
39.17
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
T378
K
S
R
I
H
Q
S
T
Y
G
K
S
L
A
I
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
T378
K
S
R
I
H
Q
S
T
Y
G
K
S
L
A
I
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
Y499
S
R
I
H
Q
S
T
Y
G
K
S
L
A
I
M
Dog
Lupus familis
XP_543550
1017
111618
T378
K
S
R
I
H
Q
S
T
Y
G
K
S
L
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
T378
K
S
R
I
H
Q
S
T
Y
G
K
S
L
A
I
Rat
Rattus norvegicus
NP_001129232
1015
111665
T378
K
S
R
I
H
Q
S
T
Y
G
K
S
L
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
T378
K
S
N
I
H
Q
S
T
Y
G
K
S
L
A
I
Frog
Xenopus laevis
Q8QFR2
1013
112021
T378
K
N
N
I
H
Q
S
T
Y
G
K
S
L
A
I
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
I378
K
N
A
I
H
Q
N
I
Y
G
K
S
L
A
I
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
I378
K
N
S
I
H
Q
N
I
Y
G
K
S
L
A
I
Fruit Fly
Dros. melanogaster
O17468
1047
113397
M375
Q
N
A
I
I
R
K
M
Y
G
K
N
Y
V
N
Honey Bee
Apis mellifera
XP_001122939
838
91355
L224
G
T
T
H
V
L
R
L
S
W
S
P
D
G
Q
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
V321
G
T
L
K
P
L
F
V
I
N
N
I
F
N
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
Y350
L
S
W
S
P
D
G
Y
S
L
F
A
C
S
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
R378
L
D
E
L
K
K
S
R
Y
G
D
V
R
G
R
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
F226
E
H
I
I
T
E
P
F
K
E
S
P
L
T
T
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
G376
I
A
A
Q
F
E
T
G
E
L
G
W
V
A
K
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
73.3
73.3
26.6
0
0
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
86.6
86.6
53.3
6.6
6.6
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
6.6
N.A.
20
13.3
6.6
P-Site Similarity:
N.A.
26.6
N.A.
33.3
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
18
0
0
0
0
0
0
0
0
6
6
59
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% C
% Asp:
0
6
0
0
0
6
0
0
0
0
6
0
6
0
0
% D
% Glu:
6
0
6
0
0
12
0
0
6
6
0
0
0
0
0
% E
% Phe:
0
0
0
0
6
0
6
6
0
0
6
0
6
0
0
% F
% Gly:
12
0
0
0
0
0
6
6
6
65
6
0
0
12
0
% G
% His:
0
6
0
12
53
0
0
0
0
0
0
0
0
0
6
% H
% Ile:
6
0
12
65
6
0
0
12
6
0
0
6
0
6
53
% I
% Lys:
53
0
0
6
6
6
6
0
6
6
59
0
0
0
6
% K
% Leu:
12
0
6
6
0
12
0
6
0
12
0
6
59
0
6
% L
% Met:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
6
% M
% Asn:
0
24
12
0
0
0
12
0
0
6
6
6
0
6
6
% N
% Pro:
0
0
0
0
12
0
6
0
0
0
0
12
0
0
0
% P
% Gln:
6
0
0
6
6
53
0
0
0
0
0
0
0
0
6
% Q
% Arg:
0
6
30
0
0
6
6
6
0
0
0
0
6
0
6
% R
% Ser:
6
42
6
6
0
6
48
0
12
0
18
53
0
6
0
% S
% Thr:
0
12
6
0
6
0
12
42
0
0
0
0
0
6
6
% T
% Val:
0
0
0
0
6
0
0
6
0
0
0
6
6
6
0
% V
% Trp:
0
0
6
0
0
0
0
0
0
6
0
6
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
65
0
0
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _